相關檔案：CSVP 387 diagnosis (with figs).pdf
387th CSVP Contributor Diagnosis
Date: Apr 22, 2022
Time: 12 : 00~16 : 00
Place: NCHU
專題演講(12:00~13:00)：美國獸醫病理專科訓練經驗分享 (陳雅媚 老師)
本次會議組織病理切片資訊： http://140.120.114.107/slidecenter.php?id=511
Case 1. CSVP 2022-3134 (NTU2021-2617, NTU GIMCP, F.H. Yang and W.H. Huang)
Feline, Russian blue, 12-year-old, castrated male. High liver index and multifocal hyperechoic nodules in liver under ultrasound were noted incidentally during health exam. The medication including antibiotics, steroids, and liver protective agents were prescribed without obvious improvement.
Morphological diagnosis: Wedge biopsy of liver:
1. Portal hepatitis, lymphocytic, multifocal, chronic, mild to moderate, with ductopenia, arteriolar and venous hyperplasia, and moderate fibrosis
2. Regeneration, centrilobular, with severe glycogenic vacuolar hepatopathy and mild bile stasis
3. Fatty change, macrovesicular form, multifocal, moderate
4. Subcapsular hepatocellular hyperplasia, multifocal, mild
IHC: CK AE1/AE3 (-)
Etiological Dx.: Feline lymphocytic cholangitis and hepatic ductopenia in a cat
Case 2. CSVP 2022-3135 (NTU2021-198, NTU GIMCP, Y.C. Lai and W.H. Huang)
Feline, Mixed, 13-year-old, neutered female. The cat presented with chronic hepatic lipidosis. A hepatic mass was incidentally noted during clinical examination. Thus, left lateral hepatic partial lobectomy was performed for histopathological examination.
Morphological diagnosis:
1. Hepatocellular carcinoma (HCC), with lipidosis, mass at the Lt. liver lobe
Laboratory examinations:
IHC: HCC: HepPar1 (+); CK7 (–)
Histochemical staining:
Trichrome staining for evaluating portal region
Etiological Dx.:
Hepatocellular Carcinoma in a Cat
Case 3. CSVP 2022-3136 (210014, NARL NLAC, T.Y. Chen and K.H. Lee)
Knockout mouse, male, 40-week-old, had the C57BL/6JNarl genetic background. The mouse was submitted for health monitoring. No gross lesions were noted from gross examination
Morphological diagnosis:
1. Atherosclerosis, extensive, moderate/severe, atherosclerotic plaques and cholesterol clefts, foamy cells within lipid rich core of atheromatous plaque and fibrosis in the tunica intima/media of aortic sinus, heart
Laboratory examinations:
The Masson’s trichrome positive staining in the atherosclerotic lesion (+)
Etiological Dx.
Atherosclerosis in ApoE-deficient mouse
Case 4. CSVP 2022-3137 (ME21036, ADDC NCYU, N.C. Twu, H.C. Kuo, and D.Y. Lo)
Suckling pigs, 4-day-old, showed clinical sign of creamy to yellowish watery diarrhea. The morbidity was about 20% and the mortality was lower than 1%.
Morphological diagnosis:
1. Enteritis (Enteropathy), acute, mild, segmental, with Gram-positive cocci adherent the luminal surface, small intestine.
Laboratory examinations:
PEDV, TGEV, SDCoV (-)
SI: Enterococcus faecalis (+)
Etiological Dx.
Enterococcus hirae Infection in Neonatal Piglet
Case 5. CSVP 2022-3138 (WA110-114, NPUST ADCC, H.Y. Lin, Y.C. Li)
Formosan Reeve's muntjac (Muntiacus reevesi micrurus), adult, showed clinical signs of weight loss, hyporexia, listless and open-mouth breathing
Morphological diagnosis:
Lung: Bronchopneumonia, necrotizing, extensive, severe, acute, with vasculitis, hemorrhage and edema
Laboratory examinations:
Burkholderia pseudomallei (+), G-
PCR:
Adenovirus, paramyxovirus, lentivirus (-)
Etiological Dx.:
Melioidosis in a Formosan Reeve's muntjac
Case 6. CSVP 2022-3139 (CP22-02001, ADDC NCHU, S.W. Yang, P.C. Liu, H.Y. Chiou, J.W. Liao, and J.H. Shien)
Mule ducks, 21-day-old, showed signs of bloody diarrhea and sudden death. The cumulative mortality from 19 to 22-day-old was about 33.5% (2,010/6,000).
Morphological diagnosis:
1. Enteritis, necro-hemorrhagic, diffuse, severe, subacute, with myriad intralesional coccidia and lymphocytic inflammation, small intestine.
2. Hepatitis, lymphoplasmacytic, local-extensive, moderate, subacute to chronic, with vacuolar degeneration, coagulative necrosis, and intralesional coccidial schizonts, liver
3. Splenitis, multifocal, mild to moderate, subacute, with lymphoid depletion and multiple coccidial schizonts, spleen.
IHC: Pax5, Iba-1 (-) MHC-II (+)
PCR: Parvovirus, DPV (-),Duck hepatitis A virus, DHAV (-)
Bact: Riemerella anatipestifer (+)
Etiological Dx.:
Systemic coccidiosis combined with infectious serositis in mule ducks