2018-6-8 CSVP 363 Diagnosis

本次會議組織病理切片資訊：

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Case 1. CSVP 2018-2989 ( NTU2014-2749, NTU, W.T. Li, H.W. Chang, C.R. Jeng, C.H. Liu, F.I. Wang, L.J. Chang, V.F. Pang)

Barbary sheep (Ammotragus lervia), 20-year-old, female. A cystic growth was noted in the anteroventral thorax and attached to the right cranial lung lobe.

Morphological diagnosis:

Thymus: The cyst wall becomes invaginated and partially encircles the solid mass of spindle-cell thymoma with formation of intratumoral cysts. The solid mass within the

thymic cyst is composed of fusiform neoplastic cells arranged in an interwoven or storiform pattern along with formation of variably sized and shaped intratumoral cysts, lined by a single layer of flattened, cuboidal to columnar epithelial cells and filled with a proteinaceous secretion.spindle cell tumor with cyst

(Journal of Veterinary Diagnostic Investigation 2016, Vol. 28(6) 744–749)

Etiological Dx.

spindle-cell thymoma and thymic cysts

Case 2. CSVP 2018-2990 (NTU2017-2722D, NTU, C.F. Kao, F.I. Wang)

Feline, 9-year-old, castrated male. The ADSH cat presented with deteriorating anorexia, weight loss and pancytopenia. Euthanasia was performed due to poor response to blood transfusion and poor outcome.

Morphological diagnosis:

Spleen: Lymphocytic depletion, with RBC autophagocytosis, histiocytosis, Prussian stain (+)

Liver: Erythrocytosis

Etiological Dx.

Hemophagocytic histiocytic sarcoma in a cat

Case 3. CSVP 2018-2991 (NTU2018-970, H.C. Yen, H.W. Chang) 

Feline, Maine coon, female, 2-year-old. The patient vomited for a week. A mass was noted on duodenum near the pylorus.

Morphological diagnosis:

1.         The tumor comprises spindle-shaped cells arranged as interlacing fascicles or in a storiform pattern with indistinct boundaries

2.         Smooth muscle: myositis, perivasculitis

3.         LN: Hyperplasia

Etiological Dx.

Gastrointestinal eosinophilic sclerosing fibroplasia

Case 4. CSVP 2018-2992 (107007-A, NTUCM LAC, Y.T. Tsai, W.P. Chen, H.W. Chen)

Mouse, FVB/N, 2-year-old, female. The mouse revealed a 2 x 1.5 x 1.5 cm, left ventrolateral cervical subcutaneous mass, and a 1.5 x 1.2 x 1.2 cm, right ventrolateral abdominal subcutaneous mass. When the brain was removed, a 0.4 x 0.3 x 0.3 cm, red-brown, spherical, well-defined mass was present in the skull base.

Morphological diagnosis:

1.     Cervical mammary gland: Adenocarcinoma, acinar subtype

2.     Abdominal mammary gland:  Adenosquamouscarcinoma

3.     Pituitary gland: Pituitary prolactinoma

4.     Brain: Vacuolation, white matter, cerebellum and brainstem

Etiological Dx.

Mammary Gland Tumor and Pituitary Adenoma in a FVB/N Mouse

Case 5. CSVP 2018-2993 (CP18-0302C, NCHU ADDC, F.Y. Tsai, C. Lin, Y.C. Wu, H.Y. Chiou, J.H. Shien) 

Chinese goslings, 6-day-old, showed anorexia, lethargy and died. There were 36, 50, 300, 300 flocks died on days 1~3, 4, 5, and 6, respectively. The cumulative mortality was 24.7% (686/2,780).

Morphological diagnosis:

1.     Enteritis, necrotizing, diffuse, severe, subacute, with intralesional intranuclear IB, small intestines

2.     Omphalitis, diffuse, severe, subacute, yolk sac and navel

3.     Myofiber degeneration and necrosis, multifocal, mild, subacute, with suspected intralesional intranuclear IB, heart

4.     Portal triditis and hepatocellular vacuolation, multifocal, mild, subacute, liver

5.     Yolk sac: Escherichia coli, Proteus mirabilis; Liver: Salmonella group B (+)

6.     Liver, spleen, pancreas and kidney: Goose Parvovirus (+)

Etiological Dx.

Goose parvarvirus

Case 6. CSVP 2018-2994(C018115, GIVPNCHU, C.W. Shu, H.P. Chung, Y.C. Wu, M.Y. Chia)  
Swine, 6-to-8-week-old, showed clinical signs of diarrhea and sunken eyes since late February, 2018. Morbidity and mortality rates were about 30% and 10%, respectively.

Morphological diagnosis:

1.         Enteritis, lymphoplasmacytic, necrotizing and edematous, subacute, diffuse, moderate, with villous atropohy, small intestine

2.         Interstitial pneumonia, proliferative, subacute, diffuse, slight to moderate, with mild bronchopneumonia and pleuritis, lungs

3.         Meningoencephalitis, lymphoplasmacytic cuffing, gliosis, multifocal, mild, cerebrum and cerebellum

Etiological Dx.