2018-1-12 CSVP 359 Diagnosis
本次會議組織病理切片資訊：
http://140.120.114.107/slidecenter.php?id=428
Case 1. CSVP 2018-2965 (WT16-038, NTU, W.T. Li, C. Lo, C.Y. Su, S. Kuo, J.H. Lin, H.W. Chang, V. F. Pang, C.R. Jeng)
Zebra Shark (Stegostoma fasciatum), 2-year-old, Female. The zebra shark was anorexic, lethargic, floating upside down, and biting its own tail. Hematology and plasma biochemistry revealed increased albumin and CPK. The animal was found dead few days later.
Morphological diagnosis:
1. Meningoencephalitis, granulocytic, locally-extensive, severe, acute to subacute, with intralesional protozoan organisms, cerebrum, cerebellum, brainstem
2. Hepatitis, necrohemorrhagic, multifocal to coalescing, moderate to severe, peracute, liver
3. Protozoan: Miamiensis avidus (syn. Philasterides dicentrarchi)
Etiological Dx.
Locally Extensive Meningoencephalitis Caused by Miamiensis avidus in a Zebra Shark
Case 2. CSVP 2018-2966 (NTU2017-0615, NTU GIMCP, C.S. Hsueh, H.W. Chang)
Canine, golden retriever, 7-year-old, female spayed. The Lt. stifle was swollen and lameness for 1-2 month. Lt. tibial bone tumor was suspected. The Lt. pelvic limb was therefore amputated.
Morphological diagnosis:
1. the primary affected region by the cellular neoplastic growth should be the synovial cavity and the neoplasm are also efface the surounding articular cartilages and invade the bone structures
2. CK (+); Vimentin (+)
Etiological Dx.
synovial cell sarcoma
Case 3. CSVP 2018-2967 (TSN17021, ADDC NCYU, P.H. Wu, H.C Kuo, C.L. Chen, Y.C. Su, M.H. Chang, D.Y. Lo)
Finishing pigs, 24-week-old, were submitted to ADDC for disease diagnosis. They showed clinical signs of depression and anorexia. The morbidity rate was 20% (375/1,875). The mortality rate was 1.92% (36/1,875)
Morphological diagnosis:
1. Spleen: necrosis, multifocal, mild, acute,
2. Skin: Dermatitis, multifocal, mild, acute with DIC diamond-skin disease
3. Heart: DIC
4. G (+), Filamentous, Erysipelothrix rhusiopathiae
Etiological Dx.
Swine Erysipelas in Finishing pig
Case 4. CSVP 2018-2968 (BM17044-a, VBTW, N.K. Yu, Y.Y. Wang, Y.C. Lai, D.Y. Luo)
Weaned pig, from a farrow-to-finish farm, showed clinical signs of paddling with legs when lying in a lateral position and nystagmus. The morbidity was 5% (15/300).
Morphological diagnosis:
1. Brain: Meningoencephalitis, purulent, diffuse, severe, acute
Etiological Dx.
Streptococcus infection in nursery pigs
Case 5. CSVP 2018-2969 (CO17-717, GIVP NCHU, J.H. Yin, Y.C. Chang. K.J. Hsu, F.T. Chan, H.Y. Chiou, J.W. Liao)
Formosan Giant Flying Squirrel, juvenile, intact male, weighing 644 g was submitted for pathological examination with a history of facture at the 3rd phalange of left forelimb. The patient had an amputation on Oct 16th, 2017, but was found dead on 31th, 2017. At necropsy, the lung lobes were diffusely mottled tan to red in color and presented heavy and wet. On the surface of lung, liver and heart had multifocal flat, irregular, pale tan to white with variable sized, measuring 0.1 × 0.1 cm – 0.2 × 0.4 cm areas.
Morphological diagnosis:
1. Liver: Hepatitis, necrotizing, histiocytic, multifocal to coalescing, subacute, severe, with abundant intra-/extrahistiocytic apicomplexan zoites , etiology consistent with Toxoplasma gondii
2. Spleen: Splenitis, necrotizing, histiocytic, multifocal to coalescing to locally extensive, subacute, severe, and lymphoid depletion, with severe lymphocytic depletion and abundant intra-/extrahistiocytic apicomplexan zoites , etiology consistent with Toxoplasma gondii
3. Mediastinal lymph node: Lymphadenitis, necrotizing, histiocytic, multifocal to coalescing, , subacute, severe, with severe lymphocytic depletion and intra-/extrahistiocytic apicomplexan zoites , etiology consistent with abundant Toxoplasma gondii
4. OCR: Primer targeting Toxoplasma gondii ITS1 gene (+)
Etiological Dx.
Systemic toxoplasmosis in a Formosan Giant Flying squirrel
Case 6. CSVP 2018-2970 (CM17-1109A,GIVP NCHU, C.L. Ho, Y.C. Wu, W.F. Chang) Finishing pigs, 34 kg in average, were sick. Clinical signs included panting and black diarrhea. The morbidity was 50%, and the mortality was 40%.
Morphological diagnosis:
1. Pneumonia, necrotizing and hemorrhagic, moderate, acute, multifocal to coalescing, with pulmonary edema, lungs.
2. Pneumonia, interstitial, lymphohistiocytic, moderate to severe, chronic, multifocal to coalescing, with mild purulent broncho-pneumonia, lungs.
3. Colitis and typhlitis, moderate, subacute, diffuse, with lymphoid depletion, colon and cecum.
4. Tonsillitis, moderate, acute, multi-focal, with lymphoid depletion, tonsil.
5. Lymphoid depletion, severe, diffuse, spleen.
Etiological Dx.
Suspected actinobacillus pleuropneumonia in finishing pigs