2017-10-13 CSVP 357 Diagnosis
本次會議組織病理切片資訊：
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CSVP 2017-2953 (NTU2016-2999, NTU, W. T. Li, C. S. Sheng, H.W. Chang, V.F. Pang, F.I. Wang, C.H. Liu, C.R. Jeng)
Feline, Persian, 14-year-old, Male. The patient showed poor appetite and activity with splenomegaly. During the splenectomy, several white to grey nodules were found on the liver, pancreas, and omentum.
Morphological diagnosis:
1. Histiocytic sarcoma, spleen/myxoid nodules
2. Ampullary/intestinal carcinoma, solid nodules
Etiological Dx.
Disseminated Histiocytic Sarcoma with Ampullary Carcinoma in a Persian Cat
Case 2. CSVP 2017-2954 (NTU2016-2539, H.C. Yen, V. F. Pang)
Canine, Corgi, male, 14-year-old. The 3rd eyelid Swollen and quickly enlarged. Cherry eye reposition surgery was performed 2 years ago. Os exenteration was performed
Morphological diagnosis:
1. Eyelid: Microscopically, a well demarcated and poorly encapsulated mass with high cellularity is noted and compresses the cornea of the eyeball . The mass is composed of neoplastic cells arranged in clusters and condensed, 1-2 layered tubular and acinar structures separated by fine fibrous stroma. Moderate to severe anisocytosis and anisokaryosis are noted. The neoplastic cells have a sphere to ellipse nuclei with 1-2 nucleoli and stipple chromatin (Fig. 5-7). Mitotic figures are about 2-3 per HPF.
2. IHC: Cytokeratin (partial +); Vimentin (+); E-Cadherin (+); Synaptophysin (-); S100 (-);
3. Special stain: Periodic acid–Schiff (+); Alcian blue (+); Fontana (-)
Etiological Dx.
Adenocarcinoma, poorly differentiated, most likely originated from the third eyelid gland, complex type, Os exenteration eyeball
Case 3. CSVP 2017-2955 (NTU2016-1824, NTU, J.Y. Peng, W.T. Li, F.I. Wang)
Canine, mixed, 14-year-old, female. OHE was performed 10 years ago; however vaginal discharge and swollen vulva were noted in recent 3 weeks. After laparotomy, a huge ovary mass (25x15x8 cm).
Morphological diagnosis:
1. Ovary: solid, whirling, stream, or pseudo rosette is occasionally noted. The neoplastic is polygonal, The neoplastic cells have an abundant to moderate amount of eosinophilic cytoplasm with indistinct cell borders a variably sized, round to oval nucleus a variably sized, round to oval nucleus
2. CD117 (C-KIT), vimentin (+);
Etiological Dx.
Dysgerminoma, the abdominal mass
Case 4. CSVP 2017-2956 (BL17019, ADDC NCYU, P. Y. Kuo, Kuo, C.L. Chen, Y.C. Su, M. H. Chang, D.Y. Lo)
Calf, Holstein, 7-day-old, female, showed clinical signs of abdominal swelling at 2 to 3 days of age. 1/15 (6.6%)
Morphological diagnosis:
1. Kidney: papillary necrosis, pelvic, focal, moderate, acute with hemorrhage.
2. Brain: purulent meningitis
3. Escherichia coli (+)
Etiological Dx.
Septicemia of Escherichia coli complicated with Nephropathy in Calf
Case 5. CSVP 2017-2957 (CO17-316, GIVP NCHU, Y. C. Tuan, C.H. Shih, J. H. Yin, J. W. Liao, H.Y. Chiou)
Green sea turtle (Chelonia mydas), intact male, 21 kg, was rescued from Peng-hu for treatment. Grossly, the turtle was in poor body condition and bleeding from eyes and nares was also noted. At postmortem the skin of neck and tail showed several raised and thick approximately 0.3-0.5 cm in diameter crater-like lesions
Morphological diagnosis:
1. Cerebrum, cerebellum and brain stem: Hemorrhage, traumatic, severe, acute
2. Brain, spleen, lung & kidney, arteries: Arteritis, moderate, chronic, multifocal, with granuloma, arterial hypertrophy, and intravascular trematode eggs (Neospirorchis sp.)
3. Skin: Dermatitis, epidermal hyperplasia and hyperkeratosis, moderate, multifocal, chronic, with extraepidermal Copepod sp. adult and eggs
4. Heart: Endocarditis, moderate, multifocal, chronic, with marked aortic intimal proliferation
Etiological Dx.
Ectoparasitosis and Spirorchidiosis in a Green sea turtle
Case 6. CSVP 2017-2958 (CO17-411, GIVP NCHU, Y.X. Lin, Y.C. Tuan, Y.H. Su, Y. C. Wu, J.W. Liao)
Mice, male, adult, unknown age, were submitted from a laboratory animal center to ADDC for disease diagnosis. In clinic, multiple yellow-brown nodules, about 0.1 x 0.2 cm, were found on the dorsal back skin of all mice.
Morphological diagnosis:
1. Hyperkeratosis, multifocal, moderate, chronic, with acanthosis, haired skin
2. Corynebacterium mastitidis
Etiological Dx.
Coryneform hyperkeratosis in mice