2017-3-10 CSVP 352 Diagnosis

本次會議組織病理切片資訊：

http://140.120.114.107/slidecenter.php?id=332       

Case 1. CSVP 2017-2923 (NTU2016-1298, NTU, S.H. Kuo, C.H. Liu)

Canine, Chihuahua, 9-year-old, castrated male. Pulmonary tumor was diagnosed in this April and complicated with severe Dirofilaria immitis infestation. After surgical extraction of the heartworms, the animal died and necropsy was performed by the referring clinician.

Morphological diagnosis:

1.     Effacing up to 95% of the sectioned pulmonary parenchyma and extensively filling the alveolar spaces with well-marked destruction of the alveoli and bronchioles, there is a poorly encapsulated, ill demarcated and regionally invasive growth.

2.     The nearby severely compressed pulmonary parenchyma shows evident aspect of atelectasis and emphysema.

3.     Besides, in the center of the tumor mass, massive coagulative necrosis and hemorrhage are apparent     

Etiological Dx.

Primary neuroendocrine carcinoma, favor small cell carcinoma, pulmonary masses with unspecified lobe location

Case 2. CSVP 2017-2924 (CS16-1204, GIVP, NCHU, F.Y. Tsai, C.H. Shih, J.W. Liao)

Canine, 3-year-old, castrated male. Chronic soft stool with blood was noted and lasted for 1 month. Canine parvovirus test was negative. No polyp and mass was found by colonoscopy, but the mucosa was edematous and reddish. Exploratory laparotomy and biopsy was performed on December 2, 2016.

Morphological diagnosis:

1.     Granulomatous colitis and granulomatous ileitis with many extracellular and intrahistiocytic algae, diffuse, mucosa and submucosa layer, chronic, severe, colon and ileum.

2.     Granulomatous lymphadenitis, diffuse, chronic, severe, lymph node.

3.     Granulomatous splenitis with hemorrhage, diffuse, chronic, severe, daughter spleen on omentum

4.     Extracellular and intrahistiocytic, round to oval, 8-20 um diameter algae that have a clear 2-4 um thick wall, and contain either central granular amphophilic material or multiple (2-8 or more) wedge-shaped endospores  (like the Mercedes Benz emblem)

5.     Stains faintly with H&E, and intensely with GMS, PAS, and Giemsa

6.     Zoonosis -In immunodeficienct patient

Etiological Dx.

Protothecosis in a dog

Case 3. CSVP 2017-2925 (CD16098, ADDC NCYU, W.H. Hsu, H.C. Kuo, C.L. Chen, Y.C. Su, M.H. Chang, D.Y. Lo)

Golden pheasant, more than 3-year-old, were sent to NCYU ADDC. These birds have showed signs of depression and emaciation since the middle of November, 2016. The morbidity rate was 32% (320/1,000). The cumulative mortality rate was 5% (50/1,000).

Morphological diagnosis:

Cecum: Severe, Multifical, Chronic-active, Heterophilic, Granulomatous, Perforated,             Parasitic, Typhlitis with Leiomyosarcoma

Etiological Dx.

Heterakis isolonche infected parasitic typhlitis with leiomyosarcoma

Case 4. CSVP 2017-2926 (WA105-233, NPUST ADDC, C.A. Yang, C.N. Lin, M.T. Chiou)

Pangolin (Manis pentadactyla), adult, female, rescued by Pingtung Rescue Center in 2015. Nasal bleeding was noted before death.

Morphological diagnosis:

1.     Multifocal, chronic active, severe, mycotic, ulcerative, esophagitis, esophagus

2.     Focal, chronic active, severe, mycotic, ulcerative, gastritis, stomach

3.     Multifocal, chronic active, mild, mycotic, glossitis, tongue

4.     Diffuse, severe, goblet cell hyperplasia, small intestine

Etiological Dx.

Candidiasis in Pangolin

Case 5. CSVP 2017-2927 (FRI 1051025A1, FRI, COA, C.Y. Deng, H.J. Ju)

Hard clam (Meretrix lusoria), showed slower growth and sporadic deaths found in culture growth stage, outbreak of mass mortality after typhoon. The accumulation mortality was 80% (160,000/200,000)

Morphological diagnosis:

Gill: bronchitis, focal to multifocal, slight

Etiological Dx.

Microcystis spp. (微囊蟲)

Case 6. CSVP 2017-2928 (2010-408-11, AHRI & NTU, Y.C. Tu, J.C. Chang, W.C. Hsu, S.C. Hu, C.J. Cheng)

Calf, yellow cattle, 1-day-old. The calf died suddenly and had a history of respiratory distress. All pulmonary lobes presented prominently mosaic pattern of light (inflated) and dark (atelectatic, uninflated).

Morphological diagnosis:

1.     Lung: Bronchopneumonia, neutrophilic and histiocytic, acute, multifocal, moderate, with intralesional squamous epithelial cells and meconium pigments, yellow calf

Etiological Dx.

Meconium aspiration pneumonia in calf