2016-11-14 CSVP 350 Diagnosis
本次會議組織病理切片資訊:
http://140.120.114.107/slidecenter.php?id=310
Case 1. CSVP 2016-2911(NTU2016-1089, NTU, H.C. Yen, C.h. Liu)
Feline, 1-year-old, male castrated. High respiratory rate and exercise intolerance were noted along with 6th grade heart murmur and lung edema
Morphological diagnosis:
1. Subaortic stenosis, with concentric ventricular hypertrophy, Lt. ventricle.
2. Myocarditis, mutifocal to coalescing, moderate to severe, chronic, with severe fibrosis and adipocytes infiltration, heart.
3. Edema, moderate to severe, with severe emphysema, congestion and excessive heart failure cells, lung.
4. Congestion, mild, liver.
Etiological Dx.
Subaortic stenosis in a cat
Case 2. CSVP 2016-2912(NTU2015-2772, NTU, C.W. Yen and H.W. Chang)
Hamster (phodopus sungorus), 2-year-old, male. A skin mass on ventral abdomen was noted about 4-5 months ago, ruptured with hemorrhage two days ago.
Morphological diagnosis:
1. Round cell tumor (sarcoma), without clear surgical margin, abdominal skin mass
Vimentin |
Diffuse nuclear + |
C-kit |
Partial cytoplasmic + |
Smooth muscle actin |
( - ) |
S-100 |
( - ) |
Androgen receptor |
Diffuse nuclear + |
Etiological Dx.
Atypical fibroma
Case 3. CSVP2016-2913(104L3749-K1, Kaohsiun City Animal Protection Office, C.H. Yang, W.C. Chen, J.P. Hsu)
Longfin batfish (platax teira) 石鯧, appeared sudden death without any clinical signs. Cumulative morbidity was 50% (6,000/12,000) in one month.
Morphological diagnosis:
1. Histopathological features of genus Megalocytiviruses were the formation of distinctive hypertrophied cells sometimes in large numbers throughout various organs, especially spleen.
2. Ranaviruses caused severe necrosis to internal organs of many fishes, especially in spleen and renal haematopoietic tissue
Etiological Dx.
Megalocytivirus and Sphaerospora co-infection in circular batfish Platax orbicularis
Case 4. CSVP2016-2914(CX16056, ADDC NCYU, W.H. Hsu, H.C. Kuo, C.L. Chen, Y.C. Su, M.H. Chang, D.Y. Lo) Chicken, Taiwan red-feather country cockerels, 20-week-old. The history showed dead cockerels were found since 15~16-week-old. Cumulative mortality was 11.6% (1,400/12,000).
Morphological diagnosis:
1. Myelocytes with obvious mitotic figure infiltrate in visceral organs and bones.
Etiological Dx.
Avian leukosis virus subgroup J infection in native chickens
Case 5. CSVP 2016-2915(T-1672, ADDC NCYU, M.Y.Chiou, H.C. Kio, C.L. Chen, Y.C.SU, M.H. Chang, D.Y.Lo)
Canine, Corgi, unknown age, male. A mass on the distal lateral skin of tibia was submitted for pathological examination on 2016/08/29
Morphological diagnosis:
1. Canine, haired skin, dermatitis, perifolliculitis, and interface mural folliculitis, ulcerative, parasitic, lymphoplasmacytic, pyogranulomatous, multifocal, chronic-active, severe, with intrafollicular mites
2. Diagnosis:
Etiological Dx.
Demodex folliculorum
Case 6 . CSVP 2016-2919 (CO16-374A, GIVP, NCHU,Y.C. Dwan, I.H. Su, P.Y. Lue, Z, P. Kao, J.W. Liao)
Guinea pig, 5-year-old, intact male, a firm mass with discharge was observed in the left testicle area.
Morphological diagnosis:
1. Fungal pneumonia, with edema and hemorrhage, multifocal to diffuse, severe, chronic, lung
Stain |
Positive/ Negative |
Cell / Structure |
Target cell |
PAS |
+ |
- |
polysaccharides |
Cytokeratin AE1/AE3 |
+++ |
cytoplasm |
Epithelial cells |
ER |
X |
nuclei |
Breast cancer tissues |
PR |
X |
nuclei |
Breast cancer tissues |
HER-2/neu |
+ |
Cell membrane |
Breast cancer tissues |
Melan-A |
+ |
cytoplasm |
Melanocytes, melanoma |
2.
Etiological Dx.
Simple Mammary Gland Adenocarcinoma and Melanoma in a Male Guinea Pig